Medical Mycology: Open Access

Current Epidemiology of Antifungal Resistance in Filamentous Fungi

Filamentous fungi are a group of pathogens that cause various diseases ranging from superficial lesions to lifethreatening invasive infections. Management of these infections relies on the use of several antifungal drugs including the most common used, azoles, echinocandins and polyenes. However, as observed in bacteria, antifungal drug resistance is emerging worldwide and represent a great concern in the control of these diseases. While reports on the resistance of Candida and Aspergillus to antifungal agents are widely available in the literature, data describing the susceptibility of dermatophytes and the nondermatophytes molds are starting to appear. This review summarizes the current situation of the antifungal drug resistance in these filamentous fungi.

Author(s): Doudou Sow1*, Khadime Sylla2, Magatte Ndiaye2, Isaac A Manga2, Souleye Lelo2, Cheikh Binetou Fall2, Roger Clement Tine2, Jean Louis Ndiaye3 and Babacar Faye2

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